There are three variables in the system tnm: tumor, lymph nodes and distant metastases. In the early stages of mesothelioma, the first stage the cells start malignant mesothelioma in order to multiply and one layer of the pleura. The pleura is the membrane that surrounds the lungs and lines the wall of the chest cavity. However, there are some cases in which pericardium (membrane surrounding the heart) and diaphragm cover is currently exploited. In this case, the cancer is still in the early stage mesothelioma.
In the second phase, the two layers of the pleura are already affected by Mesothelioma. Take note, however, that at this stage, only one side of the body affected. Pleura usually does not do much lubricating fluid that can expand and contract the lungs. The excess fluid is absorbed by blood and lymphatic vessels until there is a balance between the amount of fluid produced by and remove it. During the second stage Mesothelioma, fluid starts to take place between the membrane of the lungs and the membrane of the chest wall, resulting in pleural effusion. Increase in the volume of the liquid product of the causes of shortness of breath and chest pain. Mesothelioma other cancer patients experience dry and persistent cough. The diagnosis of pleural effusion is due to chest X-ray.
The third stage of mesothelioma means that the malignant cells that have already spread to the chest wall, lymph and one part of the chest. The patient may suffer from severe pain in the vicinity of the affected area. When not treated immediately, or when the Mesothelioma patient does not respond well to medication, and cancer has progressed to the fourth stage. The fourth stage is difficult due to mesothelioma, at this stage, entered the mesothelioma cells, blood and other organs of the body such as the liver, bones and brain. Lymph nodes on the other side of the chest can also be affected by Mesothelioma in stage IV.
Brighan a starting point, on the other hand, determines whether the Mesothelioma can be surgically removed or not and whether the lymph nodes are affected or not. Mesothelioma in the first stage, the lymph nodes are not yet affected, and the patient can still recover through surgery. In the second stage, and surgery may still be executed, but some lymph nodes have already been infiltration of cancer cells. During the third stage, the heart and chest actually affected, and even surgery is no longer desirable. Lymph nodes at this stage, however, may or may not be affected. In the final stage, the fourth stage of mesothelioma, cancer cells have already made into the bloodstream and other parts of the body such as the heart, brain, bone and liver. In most cases, the patient has reached stage IV Mesothelioma only twenty-four to four months to live